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Claravine Named a 2023 AdExchanger Programmatic Power Player

Claravine

Claravine, The Data Standards Company, has been named to AdExchanger's 2023 Programmatic Power Players List. This marks the second consecutive year Claravine has been included in the annual list. The Top 50 Programmatic Powers Players is a definitive list of the top agencies and strategic partners in the digital advertising industry. Claravine empowers a proactive approach to marketing measurement by activating data standards across people and technology – bridging the silos that limit speed and decisions. Used by Fortune 1000 companies such as Carhartt and Under Armour, Claravine’s collaborative user interface and strategic integrations with top marketing and advertising platforms enables global organizations to define, apply and connect standards across their ecosystem for faster decisions, greater agility and increased return-on-investment for their digital advertising dollars. "We are so thrilled to be recognized as a leader in the programmatic industry for the second consecutive year," said Verl Allen, CEO of Claravine. "Claravine’s mission is to take the drama out of marketing data by standardizing data at the source. This recognition is a testament to Claravine's commitment to helping organizations improve their data integrity. Claravine is proud to be a part of the programmatic advertising industry and is excited to continue helping organizations achieve their marketing goals.” As first-party data becomes paramount and demand grows for more solutions for data standardization, measurement, and personalization, Claravine sits at the source of successful outcomes for brands and marketers. By standardizing data at the source, Claravine empowers businesses to activate their own data in the most powerful and effective way possible. To further ease data usage, Claravine continues to substantially expand its integration library and be compatible with more of the major platforms powering digital advertising, including measurement solutions, creative optimization and customer data. AdExchanger’s Programmatic Power Players were chosen from the hundreds of submissions received from across the globe. A team of judges evaluated each entry based on the strength and breadth of its offerings, its documented case studies and client references. In the last year, Claravine has been recognized by AdExchanger on multiple occasions: receiving the 2022 Best Data Technology title and a 2022 AdExchanger Programmatic Power Player. Claravine was also named a cool vendor in the 2022 Gartner Cool Vendors in Marketing Data and Analytics report. About Claravine Claravine is The Data Standards Company aiming to give people, teams and technology a shared understanding of their data. Claravine helps brands and agencies deliver on the promise of modern marketing by standardizing taxonomies, naming conventions, and metadata across all digital experiences at the source of data creation. The Data Standards Cloud empowers a proactive approach to marketing metadata naming conventions and taxonomy for fast, accurate and rich business insights that help deliver the experiences customers want. Claravine partners with a quarter of the Fortune 100 to define, apply and connect standards across their ecosystem for faster decisions, greater agility, and increased ROI. Recently, Claravine was recognized by AdExchanger receiving the 2022 Best Data Technology title, a 2022 AdExchanger Programmatic Power Player and a cool vendor in the 2022 Gartner Cool Vendors in Marketing Data and Analytics report. For more information, visit www.claravine.com. Contact Details Kite Hill PR +1 704-960-2295 michael@kitehillpr.com Company Website https://www.claravine.com/

May 19, 2023 09:09 AM Eastern Daylight Time

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UAT Group Reached Agreement with Strategic Capital Partner

Umbra Applied Technologies Group, Inc.

Umbra Applied Technologies Group, Inc. (OTC: UATG) announced today that it has reached an agreement with a strategic capital partner to support the growth of its subsidiary Ossifix Orthopedics. The private equity firm specializes in the medical field. The firm’s focus provides strategic growth capital and works with existing management to increase sales, benefiting both its own investors and value for all Ossifix shareholders. As part of the agreement, the new partner will become a nine percent stakeholder in Ossifix Orthopedics and will provide up to $2 million in funding capital. The firm will also provide additional value such as its investors and relationships to include an extensive portfolio of surgeons, medical facilities and knowledgebase, which will be utilized to further expand marketing and sales for Ossifix. Chief Financial Officer, Thomas Crom stated, “Although this reduces our ownership in Ossifix it dramatically increases Ossifx capability to move forward without any dilution to UATG’s shareholders. This Ossix transaction illustrates the creative ways UATG can fund its subsidiaries without diluting its current UATG shareholders. This type of funding is complex and time-consuming but illustrates Ossifix’s intrinsic value is now being recognized by others.”. This announcement on Friday came amid growing optimism among the Company’s executives that the traction the UAT Group conglomerate has gained in the first half of the year will exceed its expectations for the year; positioning it for a remarkable year. The investment into Ossifix contributes to the Company's consolidated growth initiatives which include augmenting existing product offerings and service capabilities of its subsidiaries as well as positioning infrastructure resources in support of planned expansion. UAT Group Chairman, Alex Umbra commented, “As always, UAT Group stands ready to support each of our subsidiaries, in any way necessary, as we capitalize on the values we create together. This new relationship will not only provide strategic capital but will continue to support growth objectives that will bolster shareholder value, streamline balance sheet debt and enable verticals to be realized sooner”. About Umbra Applied Technologies Group, Inc. The firm is located in Tampa, Florida and focuses on advanced technologies across many disciplines. UAT Group is a holding company with interests in both public and private companies during the early stages of development as well as growth stages of companies with a synergistic business model to UAT Group subsidiaries. For more information, visit: www.uatgroup.com Investor and Media Contact: info@uatgroup.com For more information about Ossifix Technologies, go here: https://ossifixtech.com/ NEITHER THE SECURITIES EXCHANGE COMMISSION NOR ITS REGULATION SERVICES PROVIDER ACCEPTS RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS NEWS RELEASE. Forward-Looking Information This news release may include "forward-looking statements" including forecasts, estimates, expectations, and objectives for future operations including but not limited to its ability to conclude a business combination with a third party, sale of assets, return of capital or initial public offering and a secondary listing on the OTC as a result of aforementioned and its ability to fund the exploration of its assets through the raising of equity or debt capital or through funding by a joint venture partner that are subject to a number of assumptions, risks, and uncertainties, many of which are beyond the control of Umbra Applied Technologies Group including but not limited to capital markets and securities risks and continued development success on technology. There can be and are no actual or implied guarantees that any of the above activities will be completed or completed on terms acceptable to the Company and its shareholders or approved by any regulatory authority having jurisdiction. Such forward-looking information represents management's best judgment based on information currently available. No forward-looking statement can be guaranteed, and actual future results may vary materially. Umbra Applied Technologies Group does not assume the obligation to update any forward-looking statement, except as required by applicable law. Contact Details Umbra Applied Technologies Group, Inc. info@uatgroup.com

May 19, 2023 08:00 AM Eastern Daylight Time

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Hong Kong Startup SleekFlow Successfully Integrates GPT-4 to Drive Customer Interactions: SleekFlow AI Enables Businesses Achieve Customer Service Management and Sales Automation

Sleekflow

HONG KONG SAR - Media OutReach - 18 May 2023 - The launch of ChatGPT has led to a surge in the adoption of Generative AI in business applications, with many businesses leveraging Open AI's state-of-the-art language model to enhance their customer service, sales, and marketing strategies. SleekFlow, the SaaS omnichannel social commerce platform backed by Tiger Global, has announced the successful development of SleekFlow AI, a transformative business solution that is powered by GPT-4 technology. The startup has taken the lead in developing SleekFlow AI to assist professionals in enhancing their communication skills, maximizing their knowledge base, and developing context-aware AI-powered chatbots that deliver spot-on solutions every time. Hong Kong Startup SleekFlow Successfully Integrates GPT-4 to Drive Customer Interactions: SleekFlow AI Enables Businesses Achieve Customer Service Management and Sales Automation SleekFlow's GPT-4 Powered AI WhatsApp Chatbot Offers Personalized Recommendations and Natural Conversations for Enhanced Customer Service in Highly Customized Industries SleekFlow has developed a highly intelligent WhatsApp chatbot, integrating Azure OpenAI's GPT-4 model. With the ability to quickly respond to common customer inquiries and recommend personalized products or services based on the conversation analysis, the chatbot provides reliable and accurate responses using businesses' uploaded knowledge base as its sole information source. The customized chatbot can recognize and respond only to specific categories of questions and automatically escalate the issue to human agents for complex queries, delivering comprehensive customer service. Unlike ordinary chatbots that provide stilted answers, SleekFlow's chatbot engages in natural conversations and handles complex queries and emotions, providing personalized responses 24/7 to enhance customer experience and service efficiency. SleekFlow's founder and CEO Henson Tsai emphasized, "SleekFlow's R&D team has always focused on addressing market demand and customer pain points as the main axis for product development. The introduction of AI is particularly useful in highly customized industries, such as insurance, banking, as well as beauty and retail. For example, insurance customer service often involves a large volume of complex provisions. The GPT-4 chatbot can analyze the conversation content and insurance policies to recommend the most suitable insurance plan for customers, saving time on training human agents while ensuring responses are in accordance with the training content. The chatbot can also mark citations to enhance enterprise and customer confidence and trust. Similarly, in the beauty and retail industry, the chatbot can provide personalized product information and recommendations based on customer skin concerns, greatly improving the customer service sales process." Empowering Businesses to Deliver High-Quality Customer Service and Boost Efficiency with AI-Driven Human Agent Support SleekFlow AI provides multi-level assistance to human agents to deliver high-quality customer service. When the all-in-one omnichannel communication platform receives customer inquiries, SleekFlow AI instantly generates answers from its internal knowledge base and delivers precise recommendations to human agents based on the conversation, saving time on searching and integrating information to shorten response times. Additionally, SleekFlow AI enriches response content by providing each human agent with a dedicated AI editor, effectively avoiding grammatical errors and delivering a professional brand image. Furthermore, SleekFlow AI can translate, simplify, lengthen or even reorganize content, and apply different contextual awareness to ensure consistency and control customer service quality, ultimately reducing complaint incidents. Streamlining Business Operations Management with AI to Achieve Cost Reduction and Efficiency Improvement from Talent Training to Customer Sales SleekFlow AI offers businesses a powerful solution to break down language barriers and centralize customer service management. With its excellent language abilities, SleekFlow AI can instantly translate customer inquiries, enabling businesses to provide customer service without having to outsource overseas. Moreover, SleekFlow AI can understand and adapt to different cultural norms and communication styles, bridging cultural gaps and helping businesses expand their global reach. In addition to its customer service capabilities, SleekFlow integrates AI into its workflow to optimize internal business management. SleekFlow AI can generate concise reports from long chat threads, summarizing customer inquiries and team responses for internal recordkeeping, streamlining handover procedures and saving time on report production. The platform also allows businesses to upload documents to the database and use SleekFlow AI to assist in employee training. By quickly answering questions from a vast amount of text, SleekFlow AI enables businesses to efficiently train professional talent and shorten the learning cycle for new employees. "Over the past year, SleekFlow has experienced explosive growth, with our enterprise customers increasing sixfold, accumulating over 5,000 customers in 120 regions worldwide," says Tsai. "At the same time, we continue to optimize the platform to help businesses upgrade their customer service quality, increasing their sales converted with chat threefold and boosting the online to offline (O2O) sales by 18%. I believe that AI will be an indispensable part of business in the next three years and become the driving engine of various industries. SleekFlow AI helps businesses start using AI at a lower cost. To stay ahead of the times, you need to seize the opportunity now. We hope this upgrade will attract more enterprise customers to SleekFlow, making it the primary choice for enterprise AI transformation and driving further growth." For more information, visit https://sleekflow.io or access the full media kit (including visual assets) here. SleekFlow With our omnichannel social commerce platform, SleekFlow empowers the future of social commerce. We transform the way of business by merging chat and sales and building an unstoppable ecosystem of chat commerce. Our AI-powered Omnichannel Conversation Cloud enables a comprehensive customer journey across major social and messaging services like WhatsApp*, Facebook, Instagram, SMS, live chat, or whatever your clients prefer. We streamline the whole commerce process with social and sales all in one to breakthrough your sales growth limits. Our customer engagement solution allows businesses to enhance cross-departmental collaborations, manage all interactions with customers, blast out automated campaigns, and send payment links in chat. Conversions through conversations have never been easier. Headquartered in Hong Kong, SleekFlow raised its 8M USD Series A funding round in 2022 led by Tiger Global Capital with participation from AEF Greater Bay Area Fund, which is managed by Gobi Partners GBA and Transcend Capital Partners. Contact Details Global Head of Marketing, SleekFlow Joy Liu j.liu@sleekflow.io Brand Communications Strategist, SleekFlow Sharon Cheng s.cheng@sleekflow.io Company Website https://sleekflow.io

May 18, 2023 10:00 AM Eastern Daylight Time

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Long Live SOFR for Swaps

Tradeweb

It is officially the end of the line for LIBOR. After some 30+ years as “the world’s most important number,” and the last six years on an extended farewell tour, the London Interbank Offered Rate will officially be retired as a benchmark for U.S. dollar swaps transactions. CME Group completed its conversion to the Secured Overnight Financing Rate (SOFR) as the standard benchmark reference for over-the-counter (OTC) derivatives trades in April and LCH will complete its conversion containing U.S. dollar LIBOR vs. fixed interest rate swaps on May 20. By June, roughly $60 trillion in U.S. dollar contracts will be secured to SOFR. Regulators first announced plans to phase out LIBOR in 2017, ushering in a protracted death march that saw the slow-but-steady migration away from the decades-old benchmark. Ultimately, the Alternative Reference Rates Committee (ARRC) selected SOFR as the overnight benchmark rate to use in certain new U.S. dollar derivatives and financial contracts, and the financial industry—including regulators, central banks, trading venues and other market participants—have spent the last several years getting ready for the transition. Over the course of that multi-year migration, we’ve learned some important lessons: Big and complicated problems can be solved when the industry sets its collective mind to something. This transition was no small feat but market participants and regulators quickly rallied together to organize and coordinate efforts ahead of upcoming target deadlines. The end result was a relatively smooth process thanks to solid preparation, decisive action and regular communications. January 2022 was the moment of reckoning. Migration away from LIBOR was slow and steady before taking a drastic turn ahead of the January 2022 deadline for no new LIBOR origination. By February 2022, SOFR trading on Tradeweb made up 72% of all new risk, and across our business approximately 96% of our most active clients globally trading USD swaps were using SOFR. This playbook can be utilized elsewhere. We have been pleased to see that the insights and lessons learned from the U.S. dollar LIBOR transition have already extended beyond our markets and into non-LIBOR jurisdictions, further illustrating the permanent impact this movement has had on our global markets. Why LIBOR Was So Entrenched Getting there was no small achievement. LIBOR didn’t earn its reputation as “the world’s most important number” for nothing. As the benchmark evolved over the last three decades, it’s been sliced and diced into multiple durations and both backward-looking and forward-looking rates that are used for everything from projecting market expectations for the cost of borrowing to the underlying benchmark for U.S. dollar swaps contracts. Financial technology also grew up around LIBOR, with virtually every piece of financial services software and nearly every financial model incorporating some link to the benchmark. Thankfully, due to close collaboration between industry stakeholders including trading platforms, dealers and clients, clearinghouses and operators of order management systems, over the course of the transition period, this final step in the migration from LIBOR to SOFR in the swaps market is anticipated to be a smooth one. Orderly Transition to a New Standard In fact, much of the heavy lifting has already been done. As indicated in the chart below, the percentage of new U.S. dollar swaps trades benchmarked to SOFR and executed on the Tradeweb platform started to trend upward in August of 2021. That date followed the Commodity Futures Trading Commission’s (CFTC) Market Risk Advisory Committee (MRAC) SOFR First recommendation, which introduced a phased approach to the SOFR transition. In the following months, SOFR trading activity on the Tradeweb platform increased as clients began to offset their existing U.S. dollar LIBOR risk, with new SOFR activity reaching parity with LIBOR by January 2022, in response to the upcoming deadline which imposed restrictions on new use of U.S. dollar LIBOR. By February 2022, trading volume benchmarked to SOFR on the Tradeweb platform increased over 50% versus the previous month. In 2022 alone, we had nearly $21 trillion traded in SOFR on the platform. Together, the steady forward march toward SOFR adoption for new trades, along with the industry’s diligent efforts to smooth the migration of existing contracts benchmarked to LIBOR, has helped pave the way for an incredibly orderly transition. Following the success of the LIBOR transition in the U.S. dollar market, we’ve seen similar work being done in non-LIBOR jurisdictions, including Canada. Led by the Canadian Alternative Reference Rate Committee (CARR), Canada is shifting away from the benchmark Canadian Dollar Offered Rate (CDOR) to Canadian Overnight Repo Rate Average (CORRA) as the key Canadian interest rate benchmark. Globally, the LIBOR transition has served as a shining example of industry collaboration overcoming institutional inertia and debunking the myth that things need to be done a certain way just because that’s how they’ve always been done. It took six years and there was no shortage of doubt and concern along the way, but the transition that the New York Federal Reserve called “arguably one of the most significant and complex challenges that financial markets will ever confront,” is about to be complete. It should come as a cause for celebration to the countless market participants who weren’t afraid to tweak the process, experiment with new standards and collaborate with peers to transform and modernize critical market infrastructure. Now, as a result of this effort by so many parties, our markets are running smoothly and efficiently and we have proven once again how resilient and innovative our industry can be when we set our sights on a common goal. For our part at Tradeweb, we look forward to continuing to refine our workflows along with the some of the most accurate and timely pricing and reference data available to ensure our clients are operating in a transparent, efficient marketplace. About Tradeweb Markets Tradeweb Markets Inc. (Nasdaq: TW) is a leading, global operator of electronic marketplaces for rates, credit, equities and money markets. Founded in 1996, Tradeweb provides access to markets, data and analytics, electronic trading, straight-through-processing and reporting for more than 40 products to clients in the institutional, wholesale and retail markets. Advanced technologies developed by Tradeweb enhance price discovery, order execution and trade workflows while allowing for greater scale and helping to reduce risks in client trading operations. Tradeweb serves approximately 2,500 clients in more than 65 countries. On average, Tradeweb facilitated more than $1.1 trillion in notional value traded per day over the past four quarters. For more information, please go to www.tradeweb.com. Forward-Looking Statements This release contains forward-looking statements within the meaning of the federal securities laws. Statements related to, among other things, our outlook and future performance, the industry and markets in which we operate, our expectations, beliefs, plans, strategies, objectives, prospects and assumptions and future events are forward-looking statements. We have based these forward-looking statements on our current expectations, assumptions, estimates and projections. While we believe these expectations, assumptions, estimates and projections are reasonable, such forward-looking statements are only predictions and involve known and unknown risks and uncertainties, many of which are beyond our control. These and other important factors, including those discussed under the heading “Risk Factors” in documents of Tradeweb Markets Inc. on file with or furnished to the SEC, may cause our actual results, performance or achievements to differ materially from those expressed or implied by these forward-looking statements. Given these risks and uncertainties, you are cautioned not to place undue reliance on such forward-looking statements. The forward-looking statements contained in this release are not guarantees of future performance and our actual results of operations, financial condition or liquidity, and the development of the industry and markets in which we operate, may differ materially from the forward-looking statements contained in this release. In addition, even if our results of operations, financial condition or liquidity, and events in the industry and markets in which we operate, are consistent with the forward-looking statements contained in this release, they may not be predictive of results or developments in future periods. Any forward-looking statement that we make in this release speaks only as of the date of such statement. Except as required by law, we do not undertake any obligation to update or revise, or to publicly announce any update or revision to, any of the forward-looking statements, whether as a result of new information, future events or otherwise, after the date of this release. Contact Details Tradeweb Media Contact Daniel Noonan +1 646-767-4677 Daniel.Noonan@Tradeweb.com Company Website http://www.tradeweb.com

May 18, 2023 08:47 AM Eastern Daylight Time

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Peer To Peer Network Proudly Announces Payment Made To Tech Developers For MOBICARD 2.0 Release, Plans for Enterprise Capabilities in Version MOBICARD 2.0 Are Underway

Peer to Peer Network

Peer To Peer Network aka MOBICARD™ INC. (OTC: PTOP) (“PTOP”), a pioneering technology company specializing in digital business cards, is delighted to announce that it has come to a new agreement with the technology team thanks to a shareholder agreement with the developers by one of our shareholders “Glen”. The New agreement reads as follows: (last name redacted) “Glen agrees to compensate MOBICARD 2.0 developers $5,000 each (a total of $10,000) to move the development of MOBICARD™2.0 towards completion. Developers guarantee all functionality stipulated in the contract, emphasizing the ability to generate revenue. Upon completion and launch of MOBICARD™2.0 into the Apple and Android app stores, Glenn agrees to compensate the last and final payment of $5,000 to each developer (total of $10,000). If Glen fails to compensate at any point, the terms of the original contract (MOBICARD™2.0) between Nicholis Santana, Jay Wallace, and Peer To Peer Network will still hold.” Through this initiative, the tech development team moves up the date upon which the release of the fully functional MOBICARD™2.0 apps will be released to the app stores. Both developers have been paid the next installment of a total of $10,000, and are now on a mission to get the fully functional apps into the app stores. PTOP still plans to launch the MOBICARD™1.5 apps first in order to work out any bugs or issues prior to the fully marketable launch. This new agreement will recognize the developer’s outstanding performance and commitment to excellence and this will include competitive financial pay incentives as mentioned, performance based bonuses, and career advancement opportunities. By offering these rewards, PTOP aims to inspire continued innovation and ensure the teams dedication remains at the forefront of technological advancements. “We deeply appreciate the unwavering dedication and expertise of our tech development team,” said Joshua Sodaitis, Chairman & CEO of PTOP. “They have been instrumental in driving the development forward even after months of no pay. This payment initiative is a testament to our shareholders commitment to fostering a rewarding and collaborative work environment, as we strive to revolutionize the digital business card landscape. With this payment, we can ensure that PTOP is given apps that work properly and give us the ability to generate revenue. This will enable us to get on the path to profitability. The MOBICARD™2.0 tech development team comprises a diverse group of talented individuals, including software engineers, developers, UX/UI designers, and quality assurance professionals. Their collective expertise and collaborative efforts have been instrumental in the ongoing development, and improvements of PTOP’s MOBICARD™2.0 digital business card platform solutions. “We are happy to be able to receive this payment as a testament to the work we have already put into MOBICARD™1.5, this new agreement gives us the ability to know that we will be compensated for our time and effort. I know that both Jay & I are happy to gear up for a spectacular launch of MOBICARD™2.0 in the near future,” exclaimed Nicholis Santana of the tech development team. As an industry leader in the digital business card space, PTOP continues to leverage cutting-edge innovation to provide a secure, user-friendly, and feature-rich platform for seamless transactions. Through ongoing collaboration and the recognition of the tech development team’s contributions, MOBICARD™2.0 is poised to launch sooner and to strengthen its position as a frontrunner in the digital business card industry. Like us @MobiCard on Facebook. Follow us on Twitter @freemobicard PTOP A new phase is coming soon. Contact Info: Joshua Sodaitis, Chairman & CEO MobiCard, Inc. 45 Prospect Street Cambridge, MA 02139 Phone: 1-617-481-1971 Email: info@freemobicard.com Investor website: www.ptopnetwork.com Safe Harbor Statement: This release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The Company invokes the protections of the Private Securities Litigation Reform Act of 1995. All statements regarding our expected future financial position, results of operations, cash flows, financing plans, business strategies, products and services, competitive positions, growth opportunities, plans and objectives of management for future operations, as well as statements that include words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions are forward-looking statements. All forward-looking statements involve risks, uncertainties and contingencies, many of which are beyond our control, which may cause actual results, performance, or achievements to differ materially from anticipated results, performance, or achievements. Factors that may cause actual results to differ materially from those in the forward-looking statements include those set forth in our filings at www.sec.gov. The company is no longer a fully reporting SEC filing company. We are under no obligation to (and expressly disclaim any such obligation to) update or alter our forward-looking statements, whether as a result of new information, future events or otherwise. Contact Details MOBICARD™ INC. info@freemobicard.com Company Website https://www.freemobicard.com/

May 17, 2023 10:30 AM Eastern Daylight Time

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PathAI Announces IBD Explore, an AI-powered Histopathology Panel to Unlock Insights for Ulcerative Colitis from the Inflammatory Microenvironment

PathAI

PathAI, a global leader in AI-powered pathology, today announced the launch of IBD Explore 1, an artificial intelligence-powered panel of human interpretable features (HIFs) offering unprecedented resolution of the inflammatory microenvironment from H&E whole-slide images. IBD Explore uses more than 600 histopathology features to spatially characterize the inflammatory microenvironment, giving drug developers and clinical researchers the ability to unlock insights to inform the next phase of targeted drug development in ulcerative colitis (UC). According to the Centers for Disease Control (CDC), an increasing number of American adults have faced diagnosis of either UC or Crohn’s disease, known collectively as Inflammatory bowel disease (IBD) over the past two decades. Over the past few decades the global prevalence of UC and Crohn's disease, known collectively as inflammatory bowel disease (IBD) has increased. A Lancet study 2 found that the prevalence increased from 1990 with 79.5 per 100,000 population with IBD to 84.3 per 100,000 population in 2017. Despite this, remission rates for UC drugs have not surpassed 30% 3 and more than 30% of UC patients stop biologic therapy within 12-18 months due to lack or loss of efficacy. 4 These observations underscore the need for biomarkers such as histologic signatures to aid in drug development and patient management. Previous research found histologic measures of response to be a better predictor of drug efficacy for relapse-free survival in UC patients than endoscopy alone. 5 IBD Explore allows researchers enhanced histologic visibility, with the ability to structure and analyze spatial measures on a scalable platform, allowing insights to inform future trials. “IBD Explore provides visibility down to each individual cell in the inflammatory tissue environment and HIFs, and a level of granularity that we’ve never had,” said Andy Beck, M.D., Ph.D., chief executive officer and co-founder of PathAI. “This level of detail helps researchers identify patient subtypes and develop customized therapeutics with the hopes of greater efficacy and increased remission for UC patients.” In addition to IBD Explore, PathAI also offers automated, AI-powered Geboes scoring with its tool AI Measurement of Histological Index for Ulcerative Colitis, or AIM-HI™UC. Combined, IBD Explore and AIM-HI UC provide IBD drug developers a complete histology solution for translational research and clinical development. “The utilization of AI-powered pathology has the potential to tremendously benefit researchers in drug discovery and clinical development by reducing trial risk and enhancing therapy differentiation,” said Mike Montalto, Ph.D., chief scientific officer at PathAI. “Our suite of AI-powered solutions can reduce the noise in histological-based endpoints for IBD clinical trials and therefore isolate true drug effect. In collaboration with our biopharma partners, we aim to accelerate precision medicine options for millions of patients with UC.” To learn more about IBD Explore, visit www.IBDExplore.com Footnotes 1 IBD Explore is for research use only. Not for use in diagnostic procedures. 2 The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. October 2020. | https://doi.org/10.1016/S2468-1253(19)30333-4 3 Factors Associated with Biologic Discontinuation in Patients with Inflammatory Bowel Disease in TARGET-IBD. The American Journal of Gastroenterology 115():p S7, December 2020. | DOI: 10.14309/01.ajg.0000722904.81509.45 4 Factors Associated with Biologic Discontinuation in Patients with Inflammatory Bowel Disease in TARGET-IBD. The American Journal of Gastroenterology 115():p S7, December 2020. | DOI: 10.14309/01.ajg.0000722904.81509.45 5 Breaking the therapeutic ceiling in drug development in ulcerative colitis. May 2021. | https://doi.org/10.1016/S2468-1253(21)00065-0 About PathAI PathAI is the only AI-focused technology company to provide comprehensive precision pathology solutions from wet lab services to algorithm deployment for clinical trials and diagnostic use. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of patient samples to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. PathAI, which is headquartered in Boston, MA, and operates a CAP/CLIA-certified laboratory in Memphis, TN, is proud to be a rapidly expanding organization comprised of innovative thinkers from around the globe, For more information, please visit www.pathai.com. Contact Details SVM Public Relations and Marketing Communications Maggie Naples +1 401-490-9700 pathai@svmpr.com Company Website https://www.pathai.com/

May 17, 2023 10:00 AM Eastern Daylight Time

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Cytta Corp announces new CARES initiative to help schools in emergency situations

Cytta Corp

Cytta Corp CEO Gary Campbell and chief operating officer Natalia Sokolova joined Steve Darling from Proactive to share news about the company that has created a video and audio integration software with AI connection and advanced video compression, and portable/SaaS hardware/software systems. The software is used by police, firefighters, first responders, emergency medical workers, security, military, and their command centers. Sokolova telling Proactive the company has recently announced a partnership with First Net and Safeware Government Security Solutions. The deal means that Cytta Corp's stack will now be available to 310,000 agencies at the Federal, State, County, and Municipal levels. The company has also launched CARES for Crisis Assistance and Response for Emergency Situations initiative for school staff and administrators to react to critical emergencies within school premises. Contact Details Proactive Investors +1 604-688-8158 na-editorial@proactiveinvestors.com

May 17, 2023 09:02 AM Eastern Daylight Time

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Nextech3D.AI hits major milestone delivering over 20,000 3D models to Amazon

Nextech3D.AI

Nextech3D.AI CEO Evan Gappelberg joined Steve Darling from Proactive to share news the company achieved a major milestone producing over 20,000 thousand models with its preferred model supplier deal with Amazon. Gappelberg also shared with Proactive the company has scored a renewal contract with the largest department store in the United States for 5,000 3D models. Discussion are underway to increase that contract as well. Contact Details Proactive Investors Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

May 17, 2023 08:24 AM Eastern Daylight Time

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Vinanz eyes dual trading on US OTC market as it expands North American bitcoin mining capability

Vinanz Ltd

Vinanz executive chairman David Lenigas speaks to Proactive's Stephen Gunnion about the AQSE-listed bitcoin mining company's strategy for targeting the North American market. He says Vinanz aims to differentiate itself by focusing on decentralized mining in data centres across the US and Canada, rather than owning infrastructure or running large mining operations. While Vinanz will consider expanding into other crypt currencies, he said the prime objective is to be "spinning a couple of thousand of bitcoin miners by the end of the year." He also plans to start trading Vinanz's shares on the OTC market in the US to broaden its investor base. Contact Details Proactive UK Ltd Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

May 17, 2023 03:00 AM Eastern Daylight Time

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