News Release
Accelerating New Molecule Discovery: Rakovina Therapeutics AI Integration
Rakovina Therapeutics Inc
Rakovina Therapeutics President and Chief Science Officer Mads Daugaard and Dr. Art Cherkasov from the Vancouver Prostate Centre and UBC joined Steve Darling from Proactive to unveil an exciting collaboration agreement between Rakovina and Dr. Artem Cherkasov, granting exclusive access to the proprietary Deep Docking AI Platform for DNA-damage response targets. Dr. Cherkasov, who was appointed to Rakovina's scientific advisory board in November 2023, brings unparalleled expertise to the table. The collaboration aims to leverage the cutting-edge capabilities of the Deep Docking AI Platform, powered by advanced AI algorithms, to revolutionize the discovery and development of targeted cancer drugs. By harnessing the power of AI-driven molecular analysis, Rakovina can rapidly evaluate billions of molecular structures to identify potential candidates for targeted cancer therapy. This innovative approach enables the team to focus on DNA-damage response-related vulnerabilities, which are prevalent across various types of cancer. The Deep Docking AI Platform plays a pivotal role in this process, facilitating the rapid screening of billions of drug candidates against validated DNA-damage response targets. Through predictive modeling, the platform can assess safety, efficacy, and pharmaceutical properties, enabling Rakovina to prioritize the most promising candidates for further validation. With access to the Deep Docking AI Platform, Rakovina can expedite the drug discovery process, accelerating the transition from preclinical research to human clinical trials and potential pharmaceutical partnerships. By combining AI-driven molecular analysis with established R&D infrastructure, Rakovina aims to spearhead the development of innovative therapies that target critical vulnerabilities in cancer cells. This collaboration underscores Rakovina's commitment to advancing precision medicine and delivering groundbreaking therapies to patients in need. With the support of Dr. Cherkasov and the cutting-edge capabilities of the Deep Docking AI Platform, Rakovina is poised to make significant strides in the fight against cancer, offering hope to millions of individuals affected by this devastating disease. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com
April 02, 2024 12:49 PM Eastern Daylight Time
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News Release
Cloud DX Achieves nearly 100 % Contract Renewals worth 1.5 million in revenue
Cloud DX
Cloud DX CEO Robert Kaul joined Steve Darling from Proactive to unveil some exciting developments as the company aims for a 100% renewal rate among its clients whose contracts are expiring in the first quarter of 2024. As of the current date, 11 out of 14 potential renewals have been secured, with the remaining 3 expected to follow suit. Cloud DX specializes in executing contracts with various healthcare providers, offering Connected Health Kits that include approved medical devices and customized tablet computers. These kits are prescribed to patients for chronic care management, post-surgical recovery, remote rehabilitation, or palliative care purposes. Kaul highlighted the diverse range of clients renewing their contracts in the first quarter, including Canadian hospitals, primary care clinics in Alberta, family health teams in Ontario, community paramedic services in Ontario, the Canadian Lung Health Foundation, and a Canadian Provincial health ministry. These clients collectively enrolled approximately 2,900 unique patients in 2023. With the renewal of these contracts, Cloud DX has received orders for Connected Health Kits valued at $96,000 CAD.Furthermore, recurring subscription revenues from these contracts are projected to increase to $575,000 CAD per year, amounting to a total contract value of $1.5 million CAD by December 31, 2025. It's worth noting that Cloud DX maintains a robust gross margin of approximately 77%, as indicated in the company's most recent Financial Statements. Overall, these developments underscore Cloud DX's commitment to advancing healthcare through innovative technology solutions, while also solidifying its position as a leader in the industry. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com
April 02, 2024 12:46 PM Eastern Daylight Time
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News Release
Ramp Metals Launches Drilling Program in Pursuit of High-Grade Nickel in Saskatchewan
Ramp Metals Inc
Ramp Metals CEO Jordan Black joined Steve Darling from Proactive to introduce the company to the public domain and share exciting developments in the mining industry. With a background as a geotechnical engineer and experience in venture capital, including a notable role in taking GoldSpot public, Black has positioned Ramp Metals as a significant player in exploration, particularly focusing on nickel. In the interview with Proactive, Black highlighted the company's primary project, the Rottenstone Southwest property, located approximately 30 kilometers from the historical high-yield Rottenstone mine in Saskatchewan, renowned for its nickel production. Inspired by the success of the historical mine, Ramp Metals is committed to further exploration in this area, aiming to uncover additional high-grade nickel deposits. Preliminary geophysical surveys, notably a Time-Domain Electromagnetic (TDEM) survey, have revealed promising conductors and a magnetic structure reminiscent of significant discoveries in Australia. This discovery has garnered the attention of advisor Mark Bennett. Building on these promising findings, the company has initiated a 2000-meter drilling program, with over half already completed, targeting a principal conductor within the identified structure. This exploration effort comes at a pivotal time when high-grade nickel is in increasing demand, particularly for use in batteries, amidst dwindling supplies in North America. Ramp Metals is strategically positioned to capitalize on this growing demand and aims to contribute to the exploration and development of critical nickel resources. In summary, Ramp Metals' transition into the public domain marks an exciting chapter in its journey within the mining industry. With a focused exploration strategy, promising geophysical findings, and a dedicated team led by CEO Jordan Black, the company is poised to make significant strides in unlocking the potential of nickel resources, contributing to the growing demand for this essential commodity. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com
April 02, 2024 12:43 PM Eastern Daylight Time
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Euro Manganese achieves key milestone with environmental permit for Chvaletice Manganese Project
Euro Manganese Inc
Euro Manganese Inc President and CEO Dr Matthew James tells Proactive's Stephen Gunnion that the battery materials company has achieved a key milestone at its Chvaletice Manganese Project after receiving approval for its Environmental and Social Impact Assessment from the Czech Ministry of Environment. James told Proactive the Czech project involves remediating historical mine tailings from a previous pyrite mine, containing significant manganese deposits. The company also owns land directly opposite the tailings area for a processing plant. The Chvaletice Manganese Project is unique for its high-purity manganese, essential for electric vehicle batteries, particularly in NMC (nickel-manganese-cobalt) batteries. James explained that the project's manganese is crucial for the energy transition, boasting strong Environmental, Social, and Governance (ESG) credentials, including a carbon footprint one-third that of the industry standard in China. A completed Definitive Feasibility Study (DFS) in July 2022 estimated the project's net present value at approximately US$1.3 billion. The European Bank for Reconstruction and Development (EBRD) is the company's second-largest shareholder, highlighting significant European support alongside the European Investment Bank (EIB), which has approved the project for appraisal. Financial strategies include a proposed 65% gearing, with funding expected from both the EIB and the EBRD. Additionally, a financing package from Orion Resource Partners provides non-dilutive funding to shareholders. The company is also developing an early-stage project in Quebec, positioning itself within a growing battery materials hub. This project aims to produce IRA-compliant high-purity manganese sulphate. Upcoming milestones for investors include further offtake contracts and securing the last land access agreement for their Czech Republic project, having already achieved significant environmental approval. Contact Details Proactive North America Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com
April 02, 2024 11:01 AM Eastern Daylight Time
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Chesnara reports strong 2023 results with improved cash generation and solvency ratio
Chesnara PLC
Chesnara PLC chief executive Steve Murray discusses the company's full-year results for 2023 with Proactive's Stephen Gunnion, describing them as strong and particularly highlighting £53 million in commercial cash generation and a dividend coverage of around 150%. The company has seen a return to economic growth, with an improvement in the solvency ratio to 205%, the highest in its nearly 20-year history. New business improved to £10 million. It also completed two acquisitions this year, contributing to its M&A momentum. Chesnara announced a 3% increase in its full-year dividend to 23.97p per share, continuing a 19-year track record of increasing dividends. Operational efficiency improvements were noted, particularly in cost management, contributing to profitability. Despite economic challenges in recent years, Chesnara anticipates a more stable operating environment and is well-positioned to handle market volatility. Murray said Chesnara also plans to continue its acquisition strategy, supported by a solid balance sheet and financing options, including about £140 million in cash and a revolving credit facility. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
April 02, 2024 10:56 AM Eastern Daylight Time
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Oriole Resources outlines 2023 achievements and future exploration plans
Oriole Resources PLC
Oriole Resources PLC (AIM:ORR) CEO Tim Livesey and chief financial officer Bob Smeeton join Proactive's Stephen Gunnion with details of the company's 2023 financial and operational performance. Livesey highlighted successful exploration programs in Cameroon, at the Bibemi and Mbe projects, resulting in an enhanced main resource at Bibemi to 375,000 ounces. The latter part of the year focused on negotiations with external investors, culminating in deals with BCM for 50% ownership and $4 million investment in each of the Bibemi and Mbe licences. Smeeton detailed a £2.4 million operating loss, attributing it to non-cash items and emphasising cash preservation as a primary goal. The company secured project-level funding and a financing deal with Lanstead, providing monthly payments based on share price, which outperformed initial expectations. Looking ahead, Oriole Resources plans extensive drilling and exploration, expecting significant expansion and new resource development, with a focus on a multi-pit gold operation and centralised processing facility. Additional work includes lithium target exploration and ongoing projects in Senegal. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
April 02, 2024 10:53 AM Eastern Daylight Time
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Accesso's landmark deal with SEVEN marks strategic growth in the Saudi Market
Accesso Technology Group PLC
Accesso Technology Group PLC (AIM:ACSO, OTC:LOQPF) chief executive Steve Brown joins Proactive's Stephen Gunnion with details of a significant partnership with Saudi Entertainment Ventures (SEVEN). Brown said the collaboration highlights accesso's strategy to grow its global footprint, underlined by its 2023 acquisition of VGS, now rebranded as accesso Horizon. SEVEN, aiming to develop an expansive entertainment ecosystem across Saudi Arabia, plans to introduce over 21 attractions and more than 150 experiences across 14 cities. Horizon will be instrumental in managing admissions and entitlements for this vast project, offering comprehensive ticketing solutions and an overall visitor management system. Brown said the deal represents accesso's most substantial engagement in the Saudi market to date, providing a solid foundation for further expansion within the region. The accesso Horizon platform supports dynamic pricing, among other advanced features, aligning with SEVEN's ambitious plans. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com
April 02, 2024 10:52 AM Eastern Daylight Time
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Kuehn Law Encourages Investors of Intellia Therapeutics, Inc. to Contact Law Firm
Kuehn Law
Kuehn Law, PLLC, a shareholder litigation law firm, is investigating whether certain officers and directors of Intellia Therapeutics, Inc. (NASDAQ: NTLA ) breached their fiduciary duties to shareholders. The investigation concerns potential self-dealing. Shareholders may be entitled to damages and corporate governance reforms. If you own NTLA please contact Justin Kuehn, Esq. by email at justin@kuehn.law or call (833) 672-0814. The consultation and case are free with no obligation to you. Kuehn Law pays all case costs and does not charge its investor clients. Shareholders should contact the firm immediately as there may be limited time to enforce your rights. Why Your Participation Matters: As a shareholder your voice matters, and by getting involved, you contribute to the integrity and fairness of the financial markets. Your investment. Your voice. Your future. ™ For additional information, please visit Shareholder Derivative Litigation - Kuehn Law. Attorney advertising. Prior results do not guarantee similar outcomes. Contact Details Justin Kuehn +1 833-672-0814 justin@kuehn.law Company Website https://www.kuehn.law/
April 02, 2024 10:37 AM Eastern Daylight Time
News Release
DeFi Kingdoms Expands its Empire with Metis L2
Hercules
Today, DeFi Kingdoms’ (DFK) crown token $JEWEL launched for trading on the Metis Layer 2 network and its leading DEX, Hercules. DFK emerged on the Web3 gaming scene in 2021, when people were still learning about Web3 gaming. It’s so far garnered industry-wide attention, massive user adoption, and booming transaction volumes, earning its place among the top Web3 games and one of the most fun to play. The gaming protocol recently partnered with Metis to launch its upcoming Player vs Player Arena (PvP), known as The Colosseum, exclusively on the Metis Layer 2 network – the only L2 sharing operational control and revenue with its community via a Decentralized Sequencer. The launch of DFK token $JEWEL on Hercules boosts the already booming growth trajectory of Metis’ leading DEX. Hercules launched less than a month ago and has already amassed significant TVL, earning its place among the top dApps on Metis as the first Sustainable DeFi Liquidity Platform built for LPs. The launch of the $JEWEL/$METIS pool is the latest opportunity offered during Hercules’ Genesis Pools period, which closes on April 7. Those looking to get into Web3 gaming are encouraged to check out DeFi Kingdoms and swap into $JEWEL on Hercules DEX. Users holding $JEWEL will earn extra rewards for joining the liquidity pool, with emissions in $TORCH, xTORCH, and xMETIS. The partnership of DFK and Hercules will leverage the Metis ecosystem’s recent growth and decentralization push, creating an avenue for long-time DFK users and $JEWEL holders to onboard to Metis, and seamlessly trade $JEWEL with deep liquidity on the ecosystem’s newest and already largest DEX: Hercules. “The partnership with Metis will allow us to accelerate some timelines,” wrote DeFi Kingdoms in its recent community update. “PvP will now be brought to our players sooner and with more features than originally anticipated! Additionally, having PvP content opens opportunities for more competitive gameplay, tournaments, streaming content, additional use of in-game items such as potions, and more demand for higher-level and stronger Heroes.” Fans and players of DFK will enjoy the lower fees, faster transaction speeds, and Metis rewards distributed to further incentivize gameplay and tournaments. Metis L2 Contact: Metis on X: X.com/MetisL2 Metis on Telegram: t.me/MetisL2 Hercules DEX Contact: Twitter: x.com/theherculesdex Telegram: https://t.me/herculesdex Contact Details DeFi Kingdoms Bolon Soron bolon@kingdomstudios.io
April 02, 2024 10:30 AM Eastern Daylight Time
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